RAGE-NF-κB-PPARγ Signaling is Involved in AGEs-Induced Upregulation of Amyloid-β Influx Transport in an In Vitro BBB Model-Reference-Cited by-同舟云学术

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RAGE-NF-κB-PPARγ Signaling is Involved in AGEs-Induced Upregulation of Amyloid-β Influx Transport in an In Vitro BBB Model

Published:2017-09-04 Issue:2 Volume:33 Page:284-299
ISSN:1029-8428
Container-title:Neurotoxicity Research
language:en
Short-container-title:Neurotox Res

Author:

Chen Fang,Ghosh Arijit,Hu Mei,Long Yan,Sun Hongbin,Kong Lingyi,Hong Hao,Tang Susu

Funder

National Natural Science Foundation of China

Program for Changjiang Scholars and Innovative Research Team in University

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Springer Science and Business Media LLC

Subject

Toxicology,General Neuroscience

Link

http://link.springer.com/article/10.1007/s12640-017-9784-z/fulltext.html

Reference64 articles.

1. Arvanitakis Z, Wilson RS, Bienias JL, Evans DA, Bennett DA (2004) Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol 61:661–666

2. Biessels GJ, Reagan LP (2015) Hippocampal insulin resistance and cognitive dysfunction. Nat Rev Neurosci 16:660–671

3. Bortolotto V, Grilli M (2016) Not only a bad guy: potential proneurogenic role of the RAGE/NF-κB axis in Alzheimer’s disease brain. Neural Regen Res 11:1924–1925

4. Chen TG, Chen TL, Chang HC, Tai YT, Cherng YG, Chang YT, Chen RM (2007) Oxidized low-density lipoprotein induces apoptotic insults to mouse cerebral endothelial cells via a Bax-mitochondria-caspase protease pathway. Toxicol Appl Pharmacol 219:42–53

5. Chen YJ, Sheu ML, Tsai KS, Yang RS, Liu SH (2013) Advanced glycation end products induce peroxisome proliferator-activated receptor γ down-regulation-related inflammatory signals in human chondrocytes via toll-like receptor-4 and receptor for advanced glycation end products. PLoS One 8:66611

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