Recombinant L-HN Fusion Antigen Derived from the L and HN Domains of Botulinum Neurotoxin B Stimulates a Protective Antibody Response Against Active Neurotoxin-Reference-Cited by-同舟云学术

Recombinant L-HN Fusion Antigen Derived from the L and HN Domains of Botulinum Neurotoxin B Stimulates a Protective Antibody Response Against Active Neurotoxin

Published:2021-02-22 Issue:4 Volume:39 Page:1044-1053
ISSN:1029-8428
Container-title:Neurotoxicity Research
language:en
Short-container-title:Neurotox Res

Author:

Li Zhen,Lu Jian-Sheng,Liu Shan,Wang Rong,Xu Qing,Yu Yun-Zhou^ORCID,Yang Zhi-Xin

Funder

National Major Research and Development Program of China

Publisher

Springer Science and Business Media LLC

Subject

Toxicology,General Neuroscience

Link

https://link.springer.com/content/pdf/10.1007/s12640-021-00337-x.pdf

Reference38 articles.

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3. Barash JR, Arnon SS (2014) A novel strain of Clostridium botulinum that produces type B and type H botulinum toxins. J Infect Dis 209(2):183–191. https://doi.org/10.1093/infdis/jit449

4. Berger T, Eisenkraft A, Bar-Haim E, Kassirer M, Aran AA, Fogel I (2016) Toxins as biological weapons for terror-characteristics, challenges and medical countermeasures: a mini-review. Disaster Mil Med 2:7. https://doi.org/10.1186/s40696-016-0017-4

5. Chen C, Wang S, Wang H, Mao X, Zhang T, Ji G, Shi X, Xia T, Lu W, Zhang D, Dai J, Guo Y (2012) Potent neutralization of botulinum neurotoxin/B by synergistic action of antibodies recognizing protein and ganglioside receptor binding domain. PLoS ONE 7:e43845. https://doi.org/10.1371/journal.pone.0043845

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