Pyrroloquinoline Quinine and LY294002 Changed Cell Cycle and Apoptosis by Regulating PI3K-AKT-GSK3β Pathway in SH-SY5Y Cells-Reference-Cited by-同舟云学术

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Pyrroloquinoline Quinine and LY294002 Changed Cell Cycle and Apoptosis by Regulating PI3K-AKT-GSK3β Pathway in SH-SY5Y Cells

Published:2020-05-08 Issue:2 Volume:38 Page:266-273
ISSN:1029-8428
Container-title:Neurotoxicity Research
language:en
Short-container-title:Neurotox Res

Author:

Ji Hongyun,Ma Junxiang,Chen Li,Chen Tian,Zhang Shixuan,Jia Jiaxin,Yang Xin,Guo Caixia,Xiao Zhongxin,Niu Piye

Funder

National Natural Science Funding of China

Publisher

Springer Science and Business Media LLC

Subject

Toxicology,General Neuroscience

Link

https://link.springer.com/content/pdf/10.1007/s12640-020-00210-3.pdf

Reference26 articles.

1. Alaimo A, Gorojod RM, Kotler ML (2011) The extrinsic and intrinsic apoptotic pathways are involved in manganese toxicity in rat astrocytoma C6 cells. Neurochem Int 59(2):297–308. https://doi.org/10.1016/j.neuint.2011.06.001

2. Bryan MR, Uhouse MA, Nordham KD, Joshi P, Rose DIR, O'Brien MT et al (2018) Phosphatidylinositol 3 kinase (PI3K) modulates manganese homeostasis and manganese-induced cell signaling in a murine striatal cell line. Neurotoxicology 64:185–194. https://doi.org/10.1016/j.neuro.2017.07.026

3. Cheng H, Xia B, Su C, Chen K, Chen X, Chen P, Zou Y, Yang X (2018) PI3K/Akt signaling pathway and Hsp70 activate in hippocampus of rats with chronic manganese sulfate exposure. J Trace Elem Med Biol 50:332–338. https://doi.org/10.1016/j.jtemb.2018.07.019

4. Gong C, Liao H, Wang J, Lin Y, Qi J, Qin L, Tian LQ, Guo FJ (2012) LY294002 induces G0/G1 cell cycle arrest and apoptosis of cancer stem-like cells from human osteosarcoma via down-regulation of PI3K activity. Asian Pac J Cancer Prev 13(7):3103–3107. https://doi.org/10.7314/apjcp.2012.13.7.3103

5. Guilarte TR (2011) Manganese and Parkinson’s disease: a critical review and new findings. Cienc Saude Colet 16(11):4549–4566. https://doi.org/10.1590/s1413-81232011001200028

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