Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis-Reference-Cited by-同舟云学术

Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis

Published:2021-09-27 Issue:6 Volume:39 Page:1732-1746
ISSN:1029-8428
Container-title:Neurotoxicity Research
language:en
Short-container-title:Neurotox Res

Author:

Abdi Mahdad,Pasbakhsh Parichehr,Shabani Maryam,Nekoonam Saied,Sadeghi Asie,Fathi Fardin,Abouzaripour Morteza,Mohamed Wael,Zibara Kazem^ORCID,Kashani Iraj Ragerdi,Zendedel Adib

Funder

tehran university of medical sciences and health services

Publisher

Springer Science and Business Media LLC

Subject

Toxicology,General Neuroscience

Link

https://link.springer.com/content/pdf/10.1007/s12640-021-00417-y.pdf

Reference91 articles.

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4. Arnoux I, Willam M, Griesche N, Krummeich J, Watari H, Offermann N, Weber S, Dey PN, Chen C, Monteiro O (2018) Metformin reverses early cortical network dysfunction and behavior changes in Huntington’s disease. Elife 7:e38744

5. Aryanpour R, Pasbakhsh P, Zibara K, Namjoo Z, Boroujeni FB, Shahbeigi S, Kashani IR, Beyer C, Zendehdel A (2017a) Progesterone therapy induces an M1 to M2 switch in microglia phenotype and suppresses NLRP3 inflammasome in a cuprizone-induced demyelination mouse model. Int Immunopharmacol 51:131–139. https://doi.org/10.1016/j.intimp.2017.08.007

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