Saikosaponin-D Mitigates Oxidation in SH-SY5Y Cells Stimulated by Glutamate Through Activation of Nrf2 Pathway: Involvement of PI3K-Reference-Cited by-同舟云学术

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Saikosaponin-D Mitigates Oxidation in SH-SY5Y Cells Stimulated by Glutamate Through Activation of Nrf2 Pathway: Involvement of PI3K

Published:2022-01-07 Issue:1 Volume:40 Page:230-240
ISSN:1029-8428
Container-title:Neurotoxicity Research
language:en
Short-container-title:Neurotox Res

Author:

Du Jikun,Song Daibo,Li Yuanhua,Liu Jierong,Huang Xiaoman,Li Baohong,Li Li

Funder

Medical Scientific Research Foundation of Guangdong Province

the Project of Educational Commission of Guangdong Province

Guangdong Province Universities and Colleges Pearl River Scholar Fund

Publisher

Springer Science and Business Media LLC

Subject

Toxicology,General Neuroscience

Link

https://link.springer.com/content/pdf/10.1007/s12640-021-00438-7.pdf

Reference45 articles.

1. Ali T, Yoon GH, Shah SA, Lee HY et al (2015) Osmotin attenuates amyloid beta-induced memory impairment, tau phosphorylation and neurodegeneration in the mouse hippocampus. Sci Rep 5:11708

2. Cassano T, Pace L, Bedse G, Lavecchia AM et al (2016) Glutamate and mitochondria: two prominent players in the oxidative stress-induced neurodegeneration. Curr Alzheimer Res 13(2):185–197

3. Chen HH, Chen YT, Huang YW, Tsai HJ et al (2012) 4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling. Free Radic Biol Med 52(6):1054–1066

4. Chen Z, Zhong C (2014) Oxidative stress in Alzheimer’s disease. Neurosci Bull 30(2):271–281

5. Cui B, Zhang S, Wang Y, Guo Y (2019) Farrerol attenuates β-amyloid-induced oxidative stress and inflammation through Nrf2/Keap1 pathway in a microglia cell line. Biomed Pharmacother 109:112–119

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