Comparison of the blood-brain barrier and liver penetration of acridine antitumor drugs

Author:

Cornford Eain M.,Young Deborah,Paxton James W.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference38 articles.

1. Arlin Z (1983) Current status of amsacrine combination chemotherapy programs in acute leukemia. Cancer Treat Rep 67: 967

2. Atwell GJ, Cain BF, Seelye RN (1972) Potential antitumor agents: 12.9-Anilinoacridines. J Med Chem 15: 611

3. Atwell GJ, Rewcastle GW, Baguley BC, Denny WA (1987) Potential antitumor agents: 50. In vivo solid tumor activity of derivatives ofN-[2-(dimethylamino)ethyl]-acridine-4-carboxamide. J Med Chem 30: 664

4. Baguley BC, Denny WA, Atwell GJ, Finlay GJ, Rewcastle GW, Twigden SJ, Wilson WR (1984) Synthesis, antitumor activity and DNA binding properties of a new derivative of amsacrine,N, 5-dimethyl-9-(2-methoxy-4-methylsulfonyl-amino)-4-acridine carboxamide. Cancer Res 44: 3245

5. Bodey GP, Jacquillat C (eds) (1983) Amsacrine; current perspectives and clinical results with a new anticancer agent. Communication Media for Education, Inc., Newark, New Jersey

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