Identification of a new pharmacological activity of the phenylpiperazine derivative naftopidil: tubulin-binding drug
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Biochemistry,Biophysics
Link
http://link.springer.com/content/pdf/10.1007/s12154-014-0122-0.pdf
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3. Kanda H, Ishii K, Ogura Y, Imamura T, Kanai M et al (2008) Naftopidil, a selective alpha-1 adrenoceptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest. Int J Cancer 122:444–451
4. Hori Y, Ishii K, Kanda H, Iwamoto Y, Nishikawa K et al (2011) Naftopidil, a selective {alpha}1-adrenoceptor antagonist, suppresses human prostate tumor growth by altering interactions between tumor cells and stroma. Cancer Prev Res (Phila) 4:87–96
5. Iwamoto Y, Ishii K, Sasaki T, Kato M, Kanda H et al (2013) Oral naftopidil suppresses human renal-cell carcinoma by inducing G(1) cell-cycle arrest in tumor and vascular endothelial cells. Cancer Prev Res (Phila) 6:1000–1006
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2. Drug Repositioning of the α1-Adrenergic Receptor Antagonist Naftopidil: A Potential New Anti-Cancer Drug?;International Journal of Molecular Sciences;2020-07-27
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