Neurobehavioral effects of vigabatrin and its ability to induce DNA damage in brain cells after acute treatment in rats

Author:

Sousa Karen,Decker Natalia,Pires Thienne Rocha,Papke Débora Kuck Mausolff,Coelho Vanessa Rodrigues,Pflüger Pricila,Pereira Patrícia,Picada Jaqueline Nascimento

Funder

Fundação de Amparo a Pesquisa do Estado do Rio Grande do Sul

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference60 articles.

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2. Andreazza AC, Kauer-Sant’Anna M, Frey BN, Stertz L, Zanotto C, Ribeiro L, Giasson K, Valvassori SS, Réus GZ, Salvador M, Quevedo J, Gonçalves CA, Kapczinski F (2008) Effects of mood stabilizers on DNA damage in an animal model of mania. J Psychiatry Neurosci 33(6):516–524

3. Bolton JB, Rimmer E, Williams J, Richens A (1989) The effect of vigabatrin on brain and platelet GABA-transaminase activities. Br J Clin Pharmacol 27(Suppl. 1):35S–42S

4. Bouwman BM, van Lier H, Nitert HE, Drinkenburg WH, Coenen AM, van Rijn CM (2005) The relationship between hippocampal EEG theta activity and locomotor behaviour in freely moving rats: effects of vigabatrin. Brain Res Bull 64(6):505–509

5. Bovolenta R, Zucchini S, Paradiso B, Rodi D, Merigo F, Mora GN, Osculati F, Berto E, Marconi P, Marzola A, Fabene PF, Simonato M (2010) Hippocampal FGF-2 and BDNF overexpression attenuates epileptogenesis-associated neuroinflammation and reduces spontaneous recurrent seizures. J Neuroinflammation 7-81:1–6

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