Fragile X syndrome: a preclinical review on metabotropic glutamate receptor 5 (mGluR5) antagonists and drug development

Author:

Pop Andreea S.,Gomez-Mancilla Baltazar,Neri Giovanni,Willemsen Rob,Gasparini Fabrizio

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference120 articles.

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2. Abitbol M, Menini C, Delezoide AL, Rhyner T, Vekemans M, Mallet J (1993) Nucleus basalis magnocellularis and hippocampus are the major sites of FMR-1 expression in the human fetal brain. Nat Genet 4:147–153

3. Bakker CE, Verheij C, Willemsen R, van der Helm R, Erlemans F, Vermey M, Ygrave A, Oogeveen AT, Oostra BA (1994) Fmr1 knockout mice: a model to study fragile X mental retardation. The Dutch–Belgian Fragile X Consortium. Cell 78:23–33

4. Bear MF, Huber KM, Warren ST (2004) The mGluR theory of fragile X mental retardation. Trends Neurosci 27:370–377

5. Berry-Kravis E, Sumis A, Hervey C, Nelson M, Porges SW, Weng N, Weiler IJ, Greenough WT (2008) Open-label treatment trial of lithium to target the underlying defect in fragile X syndrome. J Dev Behav Pediatr 29:293–302

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