A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model-Reference-Cited by-同舟云学术

A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model

Published:2016-07-28 Issue:6 Volume:39 Page:807-820
ISSN:0141-8955
Container-title:Journal of Inherited Metabolic Disease
language:en
Short-container-title:J Inherit Metab Dis

Author:

Wang Fang,Travins Jeremy,Lin Zhizhong,Si Yaguang,Chen Yue,Powe Josh,Murray Stuart,Zhu Dongwei,Artin Erin,Gross Stefan,Santiago Stephanie,Steadman Mya,Kernytsky Andrew,Straley Kimberly,Lu Chenming,Pop Ana,Struys Eduard A.,Jansen Erwin E. W.,Salomons Gajja S.,David Muriel D.,Quivoron Cyril,Penard-Lacronique Virginie,Regan Karen S.,Liu Wei,Dang Lenny,Yang Hua,Silverman Lee,Agresta Samuel,Dorsch Marion,Biller Scott,Yen Katharine,Cang Yong,Su Shin-San Michael,Jin Shengfang

Funder

Agios Pharmaceuticals

Publisher

Wiley

Subject

Genetics(clinical),Genetics

Link

http://link.springer.com/content/pdf/10.1007/s10545-016-9960-y.pdf

Reference59 articles.

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5. Chen C, Liu Y, Lu C et al (2013) Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition. Genes Dev 27:1974–1985

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