Point mutation instability (PIN) mutator phenotype as model for true back mutations seen in hereditary tyrosinemia type 1

Point mutation instability (PIN) mutator phenotype as model for true back mutations seen in hereditary tyrosinemia type 1 – a hypothesis

Published:2011-10-15 Issue:3 Volume:35 Page:407-411
ISSN:0141-8955
Container-title:Journal of Inherited Metabolic Disease
language:en
Short-container-title:J Inherit Metab Dis

Author:

van Dyk Etresia,Pretorius Pieter J.

Publisher

Wiley

Subject

Genetics(clinical),Genetics

Link

http://link.springer.com/content/pdf/10.1007/s10545-011-9401-x

Reference42 articles.

1. Beckman RA (2010) Efficiency of carcinogenesis: is the mutator phenotype inevitable? Semin Cancer Biol 20:340–352

2. Bergeron A, Jorquera R, Orejuela D, Tanguay RM (2006) Involvement of endoplasmic reticulum stress in hereditary tyrosinemia type I. J Biol Chem 281:5329–5334

3. Bielas JH, Loeb KR, Rubin BP, True LD, Loeb LA (2006) Human cancers express a mutator phenotype. Proc Natl Acad Sci USA 103:18238–18242

4. Bignold LP (2006) Alkylating agents and DNA polymerases. Anticancer Res 26:1327–1336

5. Bignold LP (2007) Mutation, replicative infidelity of DNA and aneuploidy sequentially in the formation of malignant pleomorphic tumors. Histol Histopathol 22:321–326

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