We may not measure the correct intestinal wall permeability coefficient of drugs: Alternative absorptive clearance concept
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics
Link
http://link.springer.com/content/pdf/10.1007/BF02354288.pdf
Reference42 articles.
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3. G. L. Amidon, P. J. Sinko, and D. Fleisher. Estimating human fraction dose absorbed: A correlation using rat intestinal membrane permeability for passive and carrier-mediated compounds.Pharm. Res. 5:651–654 (1988).
4. W. L. Hayton. Rate-limiting barriers to intestinal drug absorption: A review.J. Pharmacokin. Biopharm. 8:321–334 (1980).
5. H. Lennernäs, O. Abrenstedt, R. Halligreen, L. Knutson, M. Ryde, and L. K. Paalzow. Regional jejunal perfusion, a newin vivo approach to study oral drug absorption in man.Pharm. Res. 9:1243–1255 (1992).
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