Biomarkers in osteoarthritis: current status and outlook — the FNIH Biomarkers Consortium PROGRESS OA study-Reference-Cited by-同舟云学术

Biomarkers in osteoarthritis: current status and outlook — the FNIH Biomarkers Consortium PROGRESS OA study

Published:2023-01-24 Issue:11 Volume:52 Page:2323-2339
ISSN:0364-2348
Container-title:Skeletal Radiology
language:en
Short-container-title:Skeletal Radiol

Author:

Hunter David J.^ORCID,Collins Jamie E.,Deveza Leticia,Hoffmann Steven C.,Kraus Virginia B.

Abstract

AbstractCurrently, no disease-modifying therapies are approved for osteoarthritis (OA) use. One obstacle to trial success in this field has been our existing endpoints’ limited validity and responsiveness. To overcome this impasse, the Foundation for the NIH OA Biomarkers Consortium is focused on investigating biomarkers for a prognostic context of use for subsequent qualification through regulatory agencies. This narrative review describes this activity and the work underway, focusing on the PROGRESS OA study.

Publisher

Springer Science and Business Media LLC

Subject

Radiology, Nuclear Medicine and imaging

Link

https://link.springer.com/content/pdf/10.1007/s00256-023-04284-w.pdf

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