CD40LG Triplication Associates with Immune Dysregulation and Exhaustion
Author:
Funder
Oulun Yliopistollinen Sairaala
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy
Link
https://link.springer.com/content/pdf/10.1007/s10875-022-01392-5.pdf
Reference5 articles.
1. Karnell JL, Rieder SA, Ettinger R, Kolbeck R. Targeting the CD40-CD40L pathway in autoimmune diseases: humoral immunity and beyond. Adv Drug Deliv Rev. 2019;141:92–103.
2. Yazdani R, Fekrvand S, Shahkarami S, Azizi G, Moazzami B, Abolhassani H, et al. The hyper IgM syndromes: epidemiology, pathogenesis, clinical manifestations, diagnosis and management. Clin Immunol. 2019;198:19–30.
3. Mehling A, Loser K, Varga G, Metze D, Luger TA, Schwarz T et al (2001) Overexpression of Cd40 ligand in murine epidermis results in chronic skin inflammation and systemic autoimmunity. J Exp Med 615–28. https://doi.org/10.1084/jem.194.5.615
4. Sun D, Le Coz C, Bunin N, Romberg N (2021) Hematopoietic stem cell transplantation successfully treats CD40LG duplication. J Clin Immunol 1668–70. https://doi.org/10.1007/s10875-021-01085-5
5. Le Coz C, Trofa M, Syrett CM, Martin A, Jyonouchi H, Jyonouchi S, et al. CD40LG duplication-associated autoimmune disease is silenced by nonrandom X-chromosome inactivation. J Allergy Clin Immunol. 2018;141:2308-11.e7.
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