Novel Mutations Causing C5 Deficiency in Three North-African Families

Author:

Colobran Roger,Franco-Jarava Clara,Martín-Nalda Andrea,Baena Neus,Gabau Elisabeth,Padilla Natàlia,de la Cruz Xavier,Pujol-Borrell Ricardo,Comas David,Soler-Palacín Pere,Hernández-González Manuel

Funder

Instituto de Salud Carlos III

Ministerio de Economía y Competitividad (ES)

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Reference27 articles.

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2. Kolev M, Le Friec G, Kemper C. Complement--tapping into new sites and effector systems. Nat Rev Immunol. 2014;14(12):811–20.

3. Merle NS, Church SE, Fremeaux-Bacchi V, Roumenina LT. Complement system part I—molecular mechanisms of activation and regulation. Front Immunol. 2015;6:262.

4. Carney DF, Haviland DL, Noack D, Wetsel RA, Vik DP, Tack BF. Structural aspects of the human C5 gene. Intron/exon organization, 5′-flanking region features, and characterization of two truncated cdna clones. J Biol Chem. 1991;266(28):18786–91.

5. Tack BF, Morris SC, Prahl JW. Fifth component of human complement: purification from plasma and polypeptide chain structure. Biochemistry. 1979;18(8):1490–7.

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