Current Status: Site-Specific Antibody Drug Conjugates

Author:

Schumacher Dominik,Hackenberger Christian P. R.,Leonhardt Heinrich,Helma JonasORCID

Funder

Deutsche Forschungsgemeinschaft

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Reference62 articles.

1. Agarwal P, Bertozzi CR. Site-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug development. Bioconjug Chem. 2015. doi: 10.1021/bc5004982 .

2. Chari RV, Miller ML, Widdison WC. Antibody-drug conjugates: an emerging concept in cancer therapy. Angew Chem Int Ed Engl. 2014;53:3796–827. doi: 10.1002/anie.201307628 .

3. Sochaj AM, Swiderska KW, Otlewski J. Current methods for the synthesis of homogeneous antibody-drug conjugates. Biotechnol Adv. 2015;33:775–84. doi: 10.1016/j.biotechadv.2015.05.001 .

4. Polakis P Antibody drug conjugates for cancer therapy. Pharmacol Rev. 2016;68:3–19. doi: 10.1124/pr.114.009373 .

5. Mathur R, Weiner GJ. Picking the optimal target for antibody-drug conjugates. Am Soc Clin Oncol Educ Book. 2013. doi: 10.1200/EdBook_AM.2013.33.e103 .

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