Clinical and immunological responses in metastatic melanoma patients vaccinated with a high-dose poly-epitope vaccine

Author:

Dangoor Adam,Lorigan Paul,Keilholz Ulrich,Schadendorf Dirk,Harris Adrian,Ottensmeier Christian,Smyth John,Hoffmann Klaus,Anderson Richard,Cripps Martin,Schneider Joerg,Hawkins Robert

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,Immunology,Immunology and Allergy

Reference31 articles.

1. King M, Spooner D, Rowlands DC (2001) Spontaneous regression of metastatic malignant melanoma of the parotid gland and neck lymph nodes: a case report and a review of the literature. Clin Oncol (R Coll Radiol) 13:466–469

2. Itoh K, Platsoucas CD, Balch CM (1988) Autologous tumor-specific cytotoxic T lymphocytes in the infiltrate of human metastatic melanomas: activation by interleukin 2 and autologous tumor cells, and involvement of the T cell receptor. J Exp Med 168:1419–1441

3. Schwartzentruber DJ, Topalian SL, Mancini M, Rosenberg SA (1991) Specific release of granulocyte-macrophage colony-stimulating factor, tumor necrosis factor-alpha, and IFN-gamma by human tumor-infiltrating lymphocytes after autologous tumor stimulation. J Immunol 146:3674–3681

4. Talebi T, Weber JS (2003) Peptide vaccine trials for melanoma: preclinical background and clinical results. Semin Cancer Biol 13:431–438

5. Pilla L, Valenti R, Marrari A, Patuzzo R, Santinami M et al (2006) Vaccination: role in metastatic melanoma. Expert Rev Anticancer Ther 6:1305–1318

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