Efficacy and safety of geptanolimab (GB226) for relapsed/refractory primary mediastinal large B-cell lymphoma: an open-label phase II study (Gxplore-003)-Reference-Cited by-同舟云学术

Efficacy and safety of geptanolimab (GB226) for relapsed/refractory primary mediastinal large B-cell lymphoma: an open-label phase II study (Gxplore-003)

Published:2023-06-08 Issue:9 Volume:72 Page:2991-3002
ISSN:0340-7004
Container-title:Cancer Immunology, Immunotherapy
language:en
Short-container-title:Cancer Immunol Immunother

Author:

Shi Yuankai^ORCID,Cui Jie,Zhou Hui,Zhang Xiaohong,Zou Liqun,Cao Junning,Gao Yuhuan,Jin Chuan,Li Xiaoling,Liu Hui,Peng Zhigang,Xie Liping,Zhang Huilai,Zhang Weihua,Zhang Hongyu,Zhong Liye,Zhou Fang,Guo Genny,He Wenduo

Funder

China and partly supported by China National Major Project for New Drug Innovation

Genor Biopharma Co., Ltd.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,Immunology,Immunology and Allergy

Link

https://link.springer.com/content/pdf/10.1007/s00262-023-03467-7.pdf

Reference40 articles.

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2. Rosenwald A, Wright G, Leroy K et al (2003) Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma. J Exp Med 198:851–862. https://doi.org/10.1084/jem.20031074

3. Savage KJ, Monti S, Kutok JL et al (2003) The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma. Blood 102:3871–3879. https://doi.org/10.1182/blood-2003-06-1841

4. Giulino-Roth L, O’Donohue T, Chen Z et al (2017) Outcomes of adults and children with primary mediastinal B-cell lymphoma treated with dose-adjusted EPOCH-R. Br J Haematol 179:739–747. https://doi.org/10.1111/bjh.14951

5. Hayden AR, Tonseth P, Lee DG et al (2020) Outcome of primary mediastinal large B-cell lymphoma using R-CHOP: impact of a PET-adapted approach. Blood 136:2803–2811. https://doi.org/10.1182/blood.2019004296