An IL-15 superagonist/IL-15Rα fusion complex protects and rescues NK cell-cytotoxic function from TGF-β1-mediated immunosuppression
Author:
Funder
National Cancer Institute
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology,Immunology,Immunology and Allergy
Link
http://link.springer.com/article/10.1007/s00262-018-2121-4/fulltext.html
Reference49 articles.
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3. Baginska J, Viry E, Paggetti J, Medves S, Berchem G, Moussay E, Janji B (2013) The critical role of the tumor microenvironment in shaping natural killer cell-mediated anti-tumor immunity. Front Immunol 4:490. https://doi.org/10.3389/fimmu.2013.00490
4. Tsushima H, Kawata S, Tamura S et al. (1996) High levels of transforming growth factor beta 1 in patients with colorectal cancer: association with disease progression. Gastroenterology. 110: 375–382
5. Ikushima H, Miyazono K (2010) TGFbeta signalling: a complex web in cancer progression. Nat Rev Cancer 10: 415–424. https://doi.org/10.1038/nrc2853
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