The integration of systemic and tumor PD-L1 as a predictive biomarker of clinical outcomes in patients with advanced NSCLC treated with PD-(L)1blockade agents
Author:
Funder
Bristol-Myers Squibb
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology,Immunology,Immunology and Allergy
Link
https://link.springer.com/content/pdf/10.1007/s00262-021-03107-y.pdf
Reference34 articles.
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2. Bocanegra A, Blanco E, Fernandez-Hinojal G et al (2020) PD-L1 in systemic immunity: unraveling its contribution to PD-1/PD-L1 blockade immunotherapy. Int J Mol Sci 21:1–17
3. Hui R, Gandhi L, Carcereny Costa E et al (2016) Long-term OS for patients with advanced NSCLC enrolled in the KEYNOTE-001 study of pembrolizumab (pembro). J Clin Oncol 34:9026–9026. https://doi.org/10.1200/jco.2016.34.15_suppl.9026
4. Hartley G, Regan D, Guth A, Dow S (2017) Regulation of PD-L1 expression on murine tumor-associated monocytes and macrophages by locally produced TNF-α. Cancer Immunol Immunother 66:523–535. https://doi.org/10.1007/s00262-017-1955-5
5. Hallqvist A, Rohlin A, Raghavan S (2020) Immune checkpoint blockade and biomarkers of clinical response in non–small cell lung cancer. Scand J Immunol 92. https://doi.org/10.1111/sji.12980
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