The strange case of TGN1412
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology,Immunology,Immunology and Allergy
Link
http://link.springer.com/content/pdf/10.1007/s00262-006-0189-8.pdf
Reference58 articles.
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3. Beyersdorf N, Hanke T, Kerkau T, Hunig T (2005) Superagonistic anti-CD28 antibodies: potent activators of regulatory T cells for the therapy of autoimmune diseases. Ann Rheum Dis 64:91–95
4. Luhder F, Huang Y, Dennehy KM, Guntermann C, Muller I, Winkler E, Kerkau T, Ikemizu S, Davis SJ, Hanke T, Hunig T (2003) Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists. J Exp Med 197:949–953
5. Lin C-H, Kerkau T, Guntermann C, Trischler M, Beyersdorf N, Scheuring Y, Tony H-P, Kneitz C, Wilhelm M, Mueller P, Huenig T, Hanke T (2004) Superagonistic anti-CD28 antibody TGN1412 as a potential immunotherapeutic for the treatment of B cell chronic lymphocytic leukemia. Blood 104:690A
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