Characterization of MHC class-I restricted TCRαβ+ CD4− CD8− double negative T cells recognizing the gp100 antigen from a melanoma patient after gp100 vaccination

Author:

Voelkl Simon,Moore Tamson V.,Rehli Michael,Nishimura Michael I.,Mackensen Andreas,Fischer Karin

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,Immunology,Immunology and Allergy

Reference45 articles.

1. Fischer K, Voelkl S, Heymann J, Przybylski GK, Mondal K, Laumer M, Kunz-Schughart L, Schmidt CA, Andreesen R, Mackensen A (2005) Isolation and characterization of human antigen-specific TCR alpha beta+ CD4–CD8- double-negative regulatory T cells. Blood 105:2828–2835

2. Zinkernagel RM, Doherty PC (1997) The discovery of MHC restriction. Immunol Today 18:14–17

3. Sprent J, Schaefer M, Lo D, Korngold R (1986) Functions of purified L3T4+ and Lyt-2+ cells in vitro and in vivo. Immunol Rev 91:195–218

4. Nishimura MI, Avichezer D, Custer MC, Lee CS, Chen C, Parkhurst MR, Diamond RA, Robbins PF, Schwartzentruber DJ, Rosenberg SA (1999) MHC class I-restricted recognition of a melanoma antigen by a human CD4+ tumor infiltrating lymphocyte. Cancer Res 59:6230–6238

5. Takahama Y, Kosugi A, Singer A (1991) Phenotype, ontogeny, and repertoire of CD4–CD8- T cell receptor alpha beta+ thymocytes. Variable influence of self-antigens on T cell receptor V beta usage. J Immunol 146:1134–1141

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