An HER2 DNA vaccine with evolution-selected amino acid substitutions reveals a fundamental principle for cancer vaccine formulation in HER2 transgenic mice-Reference-Cited by-同舟云学术

An HER2 DNA vaccine with evolution-selected amino acid substitutions reveals a fundamental principle for cancer vaccine formulation in HER2 transgenic mice

Published:2019-06-08 Issue:7 Volume:68 Page:1143-1155
ISSN:0340-7004
Container-title:Cancer Immunology, Immunotherapy
language:en
Short-container-title:Cancer Immunol Immunother

Author:

Jones Richard F.,Reyes Joyce D.,Gibson Heather M.,Jacob Jennifer B.,Vaishampayan Ulka,Ratner Stuart,Chen Kang,Wei Wei-Zen

Funder

Helen Kay Memorial Trust

Herrick Foundation

National Cancer Institute

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,Immunology,Immunology and Allergy

Link

http://link.springer.com/content/pdf/10.1007/s00262-019-02333-9.pdf

Reference48 articles.

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2. Lohmueller J, Finn OJ (2017) Current modalities in cancer immunotherapy: immunomodulatory antibodies. CARs and vaccines. Pharmacol Ther 178:31–47. https://doi.org/10.1016/j.pharmthera.2017.03.008

3. Harari D, Yarden Y (2000) Molecular mechanisms underlying ErbB2/HER2 action in breast cancer. Oncogene 19:6102–6114. https://doi.org/10.1038/sj.onc.1203973

4. Moasser MM (2007) The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis. Oncogene 26:6469–6487. https://doi.org/10.1038/sj.onc.1210477

5. Taylor C, Hershman D, Shah N et al (2007) Augmented HER-2 specific immunity during treatment with trastuzumab and chemotherapy. Clin Cancer Res 13:5133–5143. https://doi.org/10.1158/1078-0432.CCR-07-0507

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