1. P. Sims andP. L. Grover, Adv. Cancer Res.20, 165 (1974).
2. For structure-activity relationships of chemical carcinogens in the aromatic polycyclic series, seeJ. C. Arcos andM. F. Argus,Chemical Induction of Cancer (Academic Press, New York 1974), vol. 2A, p. 1.
3. E. C. Miller andJ. A. Miller, Cancer. Res.20, 133 (1960).
4. J. A. Miller andE. C. Miller, Cancer Res.23, 229 (1963).
5. For the rationale underlying this approach seeM. S. Newman, inChemical Carcinogenesis (Marcel Dekker, New York 1974), p. 177.