Pharmaceutical development of a parenteral formulation of the novel anti-tumor agent carzelesin (U-80,244)

Author:

Jonkman de Vries Jantine D.,de Graaff-Teulen Marga J. A.,Henrar Roland E. C.,Kettenes van den Bosch Jantien J.,Bult Auke,Beijnen Jos H.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Reference23 articles.

1. Beijnen JH: New cytotoxic drugs and targets in oncology. Pharm Weekbl [Sci] 14:258?267, 1992

2. Reynolds VL, McGovern JP, Hurley LH: The chemistry, mechanism of action and biological properties of CC-1065, a potent antitumor antibiotic. J Antibiot (Tokyo) 39:319?334, 1986

3. Wierenga W, Bhuyan BK, Kelly RC, Krueger WC, Li LH, McGovern JP, Swenson DH, Warpehoski MA: Antitumor activity and biochemistry of novel analogs of the antibiotic, CC-1065. Adv Enzyme Regul 25:141?155, 1986

4. Li LH, Wallace TL, DeKoning TF, Warpehoski MA, Kelly RC, Prairie MD, Krueger WC: Structure and activity relationship of several novel CC-1065 analogs. Invest New Drugs 5:329?337, 1987

5. Li LH, DeKoning TF, Kelly RC, Krueger WC, McGovern JP, Padbury GE, Petzold GL, Wallace TL, Ouding RJ, Prairie MD, Gebhard I: Cytotoxicity and antitumor activity of carzelesin, a prodrug cyclopyrroloindole analog. Cancer Res 52:4909?4913, 1992

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