Thermo-reversible flurbiprofen liquid suppository with HP-β-CD as a solubility enhancer: improvement of rectal bioavailability

Author:

Kim Jin-Ki,Kim Myung-Sun,Park Jeong-Sook,Kim Chong-Kook

Publisher

Springer Science and Business Media LLC

Subject

Condensed Matter Physics,General Chemistry,Food Science

Reference35 articles.

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2. Brown, B.L., Johnson, J.H., Hearron, M.S.: Double-blind comparison of flurbiprofen and sulindac for the treatment of osteoarthritis. Am. J. Med. 80, 112–117 (1986). doi: 10.1016/0002-9343(86)90126-9

3. Richy, F., Rabenda, V., Mawet, A., Reginster, J.Y.: Flurbiprofen in the symptomatic management of rheumatoid arthritis: a valuable alternative. Int. J. Clin. Pract. 61, 1396–1406 (2007). doi: 10.1111/j.1742-1241.2007.01452.x

4. Dalvi, S.S., Gupta, K.C., Pohujani, S.M., Vaidya, A.B., Satoskar, R.S.: Bioavailability of aspirin after oral and rectal administration in volunteers and patients with fever. J. Postgrad. Med. 31, 192–195 (1985)

5. Insel, P.A.: Analgesic-antipyretic and antiinflammatory agents and drugs employed in the treatment of gout. In: Hardman, J.G., Limbird, I.E. (eds.) Goodman & Gilman’s the pharmacological basis of therapeutics, pp. 617–658. McGraw-Hill, New York (1996)

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