Influence of alkene substituent in dictating the reaction course to form carbocycles or oxacycles during ring closing metathesis of acyclic trienes

Author:

Datta Ritabrata,Ghosh SubrataORCID

Funder

SERB J. C. Bose National Fellowship

Indian National Science Academy

Publisher

Springer Science and Business Media LLC

Subject

General Chemistry

Reference9 articles.

1. For excellent accounts on RCM see: (a) Grubbs R H, Miller S J and Fu G C 1995 Ring-Closing Metathesis and Related Processes in Organic Synthesis Acc. Chem. Res. 28 446; (b) Fürstner A 1997 Recent advancements in Ring Closing Olefin Metathesis Top. Catal. 4 285; (c) Schuster M and Blechert S 1997 Olefin Metathesis in Organic Chemistry Angew. Chem. Int. Ed. 36 2036; (d) Grubbs R H and Chang S 1998 Recent Advances in Olefin Metathesis and Its Application in Organic Synthesis Tetrahedron 54 4413; (e) Armstrong S K 1998 Ring Closing Diene Metathesis in Organic Synthesis J. Chem. Soc. Perkin Trans. 1 371; (f) Fürstner A 2000 Olefin Metathesis and Beyond Angew. Chem. Int. Ed. 39 3012; (g) Kotha S and Sreenivasachary N 2001 Catalytic Metathesis Reaction in Organic Synthesis Indian J. Chem. B40 763; (h) Deiters A and Martin S F 2004 Synthesis of Oxygen- and Nitrogen-Containing Heterocycles by Ring-Closing Metathesis Chem. Rev. 104 2199; (i) Nicolaou K C, Bulger P G and Sarlah D 2005 Metathesis Reactions in Total Synthesis Angew. Chem. Int. Ed. 44 4490; (j) Ghosh S, Ghosh S and Sarkar N 2006 Factors Influencing Ring Closure Through Olefin Metathesis-A Perspective J. Chem. Sci. 118 223; (k) Chattopadhyay S K, Karmakar S, Biswas T, Majumdar K C, Rahaman H and Roy B 2007 Formation of Medium-Ring Heterocycles by Diene and Enyne Metathesis Tetrahedron 63 3919

2. Ghosh S, Ghosh S and Sarkar N 2006 Factors Influencing Ring Closure Through Olefin Metathesis-A Perspective J. Chem. Sci. 118 223

3. (a) Maity S, Matcha K and Ghosh S 2010 Synthetic Studies on Schisandra Nortriterpenoids. Stereocontrolled Synthesis of Enantiopure C-5-epi ABC Ring Systems of Micrandilactone A and Lancifodilactone G Using RCM J. Org. Chem. 75 4192; (b) Mondal S, Yadav R N and Ghosh S 2011 Influence of Diene Substituent Position on the Stereochemical Outcome in IMDA Reaction of Decatrienones. An Asymmetric Synthesis of $$\text{C}_{10}$$ C 10 -epi-Dihydro-epi-deoxy Arteannuin B Org. Lett. 13 6078; (c) Bose S, Ghosh M and Ghosh S 2012 Domino Ring-Opening Metathesis-Ring-Closing Metathesis of Bicyclo[2.2.2]octene Derivatives: Scope and Limitations J. Org. Chem. 77 6345; (d) Datta R and Ghosh S 2017 Total Synthesis of the Marine Polyketide (-)-Gracilioether F J. Org. Chem. 82 7675

4. (a) Festa C, Lauro G, Marino S D, D’Auria M V, Monti M C, Casapullo A, D’Amore C, Renga, B, Mencarelli A, Petek S, Bifulco G, Fiorucci S and Zampella A 2012 Plakilactones from the Marine Sponge Plakinastrella mamillaris. Discovery of a New Class of Marine Ligands of Peroxisome Proliferator-Activated Receptor $$\gamma $$ γ J. Med. Chem. 55 8303; (b) Norris M D and Perkins M V 2016 Total Synthesis of Plakilactones C, B and des-Hydroxyplakilactone B by the Oxidative Cleavage of Gracilioether Furanylidenes J. Org. Chem. 81 6848

5. (a) Baylon C, Heck M-P and Mioskowski C 1999 Bis Ring Closing Olefin Metathesis for the Synthesis of Unsaturated Polycyclic Ethers. O-Membered Ring Cyclization in Favor of C-Membered Ring Cyclization J. Org. Chem. 64 3354; (b) Heck M-P, Baylon C, Nolan S P and Mioskowski C 2001 Triple Ring Closing Metathesis Reaction: synthesis of Adjacent Cyclic Ethers Org. Lett. 3 1989

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