Generation of lymphokine activated killer cells in a new high density dialyzing culture apparatus

Author:

Kohgo Yutaka,Sakamaki Sumio,Kanisawa Yuji,Nojiri Shuichi,Ueno Yoshinori,Itoh Yoshinori,Takahashi Minoru,Sasagawa Yutaka,Hosoi Shinji,Sato Seiji,Niitsu Yoshiro

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Clinical Biochemistry,Biomedical Engineering,Bioengineering,Biotechnology

Reference16 articles.

1. Adler A, Chervenick PA, Whitesilde TL, Lotzova E and Herbermann RB (1988) Interleukin 2 induction of lymphokine-activated killer (LAK) activity in the peripheral blood and bone marrow of acute leukemia patients. 1. Feasibility of LAK generation in adult patients with active disease and in remission. Blood 71: 709?716.

2. Alter BJ, Ochoa AC, Gruenberg M, Keyport GM and Bach FH (1987) The growth of cells with LAK activity in an automated tissue culture system (Acusyst P). Prog. Clin. Biol. Res. 244: 301?311.

3. Grimm EA, Mazunider M, Zhang HZ and Rosenberg SA (1982) Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin-2 activated autologous human peripheral blood lymphocytes. J. Exp. Med. 155: 1823?1841.

4. Hinuma S, Naruo O, Shiho O and Tsukamoto K (1986) Characteristics of murine non-specific killer cells induced in vivo by recombinant human interleukin 2. Immunology 59: 251?259.

5. Itoh K, Tilden AB, Kumagai K and Balch CM (1985) Leu 11+ lymphocytes with natural killer (NK) activity are precursors of recombinant interleukin 2 (rIL-2) induced activated killer (AK) cells. J. Immunol. 134: 802?807.

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