Critical Analysis of cGMP Large-Scale Expansion Process in Bioreactors of Human Induced Pluripotent Stem Cells in the Framework of Quality by Design-Reference-Cited by-同舟云学术

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Critical Analysis of cGMP Large-Scale Expansion Process in Bioreactors of Human Induced Pluripotent Stem Cells in the Framework of Quality by Design

Published:2021-11 Issue:6 Volume:35 Page:693-714
ISSN:1173-8804
Container-title:BioDrugs
language:en
Short-container-title:BioDrugs

Author:

Rivera-Ordaz Araceli,Peli Valeria,Manzini Paolo,Barilani Mario^ORCID,Lazzari Lorenza

Funder

Fondazione Regionale per la Ricerca Biomedica, Regione Lombardia

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine,Biotechnology

Link

https://link.springer.com/content/pdf/10.1007/s40259-021-00503-9.pdf

Reference135 articles.

1. Takahashi K, et al. Induction of pluripotent stem cells from fibroblast cultures. Nat Protoc. 2007;2(12):3081–9.

2. Karagiannis P, et al. Induced Pluripotent stem cells and their use in human models of disease and development. Physiol Rev. 2019;99(1):79–114.

3. Rowe RG, Daley GQ. Induced pluripotent stem cells in disease modelling and drug discovery. Nat Rev Genet. 2019;20(7):377–88.

4. Elitt MS, Barbar L, Tesar PJ. Drug screening for human genetic diseases using iPSC models. Hum Mol Genet. 2018;27(R2):R89–98.

5. Raya A, et al. A protocol describing the genetic correction of somatic human cells and subsequent generation of iPS cells. Nat Protoc. 2010;5(4):647–60.

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