MTHFR C677T Polymorphism, Plasma Homocysteine, and PDGF-AA Levels and Transcranial Doppler Velocity in Children With Sickle Cell Disease

Author:

Mahmoud Asmaa A.,El Hady Nahla M. S. Abd,Rizk Mohammed S.,El-Hawwary Ahmed M.,Saleh Nagwan Y.

Publisher

Springer Science and Business Media LLC

Subject

Pediatrics, Perinatology and Child Health

Reference15 articles.

1. Rees DC, Williams TN, Gladwin MT. Sickle-cell disease. Lancet. 2010;376:2018–31.

2. DeBaun MR, Kirkham FJ. Central nervous system complications and management in sickle cell disease. Blood. 2016;127:829–38.

3. SatiAbbas S, Abul–Razak N, Mustafa N, et al. Homocysteine, folic acid, vitamin B12 and pyridoxine: effects on vaso-occlusive crisis in sickle cell anemia and sickle–thalassemia. Iraqi Postgraduate Medical Journal. 2011;10:473–9.

4. Greenland P, Alpert JS, et al. American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. 2010 ACCF/AHA Guideline for Assessment of Cardiovascular Risk on Asymptomatic Adults. Circulation. 2010;122:e584–636.

5. Hyacinth HI, Adams RJ, Voeks JH, et al. Frequent red cell transfusions reduced vascular endothelial activation and thrombogenicity in children with sickle cell anemia and high stroke risk. Am J Hematol. 2014;89:47–51.

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