Präklinische Studien zum Einfluss des Tyrosinkinaseinhibitors AEE788 auf die Malignität des Nierenzellkarzinoms
Author:
Publisher
Springer Science and Business Media LLC
Subject
Urology
Link
http://link.springer.com/content/pdf/10.1007/s00120-008-1831-1.pdf
Reference22 articles.
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2. Garcia JA, Rini BI (2007) Recent progress in the management of advanced renal cell carcinoma. CA Cancer J Clin 57: 112–125
3. Bellmunt J, Montagut C, Albiol S et al. (2007) Strategies in the treatment of metastatic renal cell carcinoma: an update on molecular targeting agents. BJU Int 99: 274–280
4. Traxler P, Allegrini PR, Brandt R et al. (2004) AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity. Cancer Res 64: 4931–4941
5. Yu C, Friday BB, Lai JP et al. (2007) Abrogation of MAPK and Akt signaling by AEE788 synergistically potentiates histone deacetylase inhibitor-induced apoptosis through reactive oxygen species generation. Clin Cancer Res 13: 1140–1148
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