Left ventricular thrombus
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11936-001-0025-6.pdf
Reference35 articles.
1. van Dantzig JM, Delemarre BJ, Bot H, et al.: Left ventricular thrombus in acute myocardial infarction. Eur Heart J 1996, 17:1640–1645.
2. Keren A, Goldberg S, Gottlieb S, et al.: Natural history of left ventricular thrombi: their appearance and resolution in the posthospitalization period of acute myocardial infarction. J Am Coll Cardiol 1990, 15:790–800. The authors describe the natural history of LVT following acute MI in 198 consecutive patients, 34 of whom received thrombolytic therapy. This large series of patients was prospectively followed with echocardiography for an average of 2 years following infarction. Anterior infarction, ejection fraction less than or equal to 35%, and apical dyskinesis were predictive of LVT development. Nearly half of the patients with thrombus had resolution of thrombus 6 months after infarction. Resolution of thrombus was associated with akinesia rather than dyskinesia at hospital discharge and warfarin treatment. LVT developed after discharge in about 10% of patients and was related to deterioration in left ventricular function, ejection fraction less than or equal to 35% before discharge, and ventricular aneurysm or dyskinesia. These observations have established the natural history of LVT and provide the rational for anticoagulation therapy recommendations.
3. Vaitkus PT, Barnathan ES: Embolic potential, prevention and management of mural-thrombus complicating anterior myocardial infarction: a metaanalysis. J Am Coll Cardiol 1993, 22:1004–1009.
4. Roberts WC, Siegal RJ, McManus BM: Idiopathic dilated cardiomyopathy: analysis of 152 necropsy patients. Am J Cardiol. 1987, 60:1340–55.
5. Tanne D, Gottlieb S, Hod H, et al.: Incidence and mortality from early stroke associated with acute myocardial infarction in the prethrombolytic and thrombolytic eras. J Am Coll Cardiol 1997, 30:1484–1490.
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