Deep venous thrombosis and pulmonary embolism
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11936-002-0003-7.pdf
Reference33 articles.
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2. Hull RD, Raskob GE, Hirsh J, et al.: Continuous intravenous heparin compared with intermittent subcutaneous heparin in the initial treatment of proximal-vein thrombosis. N Engl J Med 1986, 315:1109–1114.
3. Prandoni P, Lensing AWA, Cogo A, et al.: The long-term clinical course of acute deep venous thrombosis. Ann Intern Med 1996, 125:1–7.
4. Schulman S, Rhedin A-S, Lindmaker P, et al.: A comparison of six weeks with six months of oral anticoagulant therapy after a first episode of venous thromboembolism. N Engl J Med 1995, 332:1661–1665.
5. Decousus H, Leizorovicz A, Parent F, et al.: A clinical trial of vena caval filters in the prevention of pulmonary embolism in patients with proximal deep-vein thrombosis. N Engl J Med 1998, 338:409–415. This is the only randomized trial of IVC filter use in patients with DVT. Patients were randomized to IVC filter placement plus anticoagulation or to anticoagulation alone. The results demonstrated effective prevention of PE (1.1% vs 4.8%) at 12 days of follow-up. However, there was no difference in the rate of symptomatic PE at 2 years of follow-up (3.4% vs 6.3%) but there was a significantly increased incidence of recurrent DVT (20.8% vs 11.6%).
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