Possible Treatment Strategies for Portal Hypertension in Liver Cirrhosis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Virology,Hepatology
Link
http://link.springer.com/content/pdf/10.1007/s11901-016-0321-y.pdf
Reference79 articles.
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2. ••Mederacke I, Hsu CC, Troeger JS, Huebener P, Mu X, Dapito DH, et al. Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology. Nat Commun. 2013;4:2823. This work demonstrates the prominent and pivotal role of activated hepatic stellate cells in liver fibrogenesis.
3. Baba TT, Ohara-Nemoto Y, Miyazaki T, Nemoto TK. Involvement of geranylgeranylation of Rho and Rac GTPases in adipogenic and RANKL expression, which was inhibited by simvastatin. Cell Biochem Funct. 2013;31:652–9.
4. Veillard NR, Braunersreuther V, Arnaud C, Burger F, Pelli G, Steffens S, et al. Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages. Atherosclerosis. 2006;188:51–8.
5. Trebicka J, Hennenberg M, Laleman W, Shelest N, Biecker E, Schepke M, et al. Atorvastatin lowers portal pressure in cirrhotic rats by inhibition of RhoA/Rho-kinase and activation of endothelial nitric oxide synthase. Hepatology. 2007;46:242–53.
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