Recent advances in tau-directed immunotherapy against Alzheimer’s disease: an overview of pre-clinical and clinical development-Reference-Cited by-同舟云学术

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Recent advances in tau-directed immunotherapy against Alzheimer’s disease: an overview of pre-clinical and clinical development

Published:2020-07-06 Issue:7 Volume:35 Page:1049-1066
ISSN:0885-7490
Container-title:Metabolic Brain Disease
language:en
Short-container-title:Metab Brain Dis

Author:

Ng Pei Ying,Chang I Shuen,Koh Rhun Yian,Chye Soi Moi

Funder

Fundamental Research Grant Scheme

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Biochemistry

Link

https://link.springer.com/content/pdf/10.1007/s11011-020-00591-6.pdf

Reference117 articles.

1. Agadjanyan MG, Zagorski K, Petrushina I, Davtyan H, Kazarian K, Antonenko M, Davis J, Bon C, Blurton-Jones M, CRibbs DH, Ghochikryan A (2017) Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency. Mol Neurodegener 12:33. https://doi.org/10.1186/s13024-017-0172-1

2. Ahmad ZA, Yeap SK, Ali AM, Ho WY, Alitheen NB, Hamid M (2012) scFv antibody: principles and clinical application. Clin Dev Immunol 2012:980250. https://doi.org/10.1155/2012/980250, 1, 15

3. Alonso A, Zaidi T, Novak M, Grundke-Iqbal I, Iqbal K (2001) Hyperphosphorylation induces self-assembly of into tangles of paired helical filaments/straight filaments. Proc Natl Acad Sci 98:6923–6928. https://doi.org/10.1073/pnas.121119298

4. Alam R, Driver D, Wu S, Lozano E, Key SL, Hole JT, Hayashi ML, Lu J (2017) Preclinical characterization of an antibody [LY3303560] targeting aggregated tau. Alzheimers Dement 13:592–593. https://doi.org/10.1016/j.jalz.2017.07.227

5. Albert M, Mairet-Coello G, Danis C, Lieger S, Caillierez R, Carrier S, Skrobala E, Landrieu I, Michel A, Schmitt M, Citron M, Downey P, Courade JP, Buée L, Colin M (2019) Prevention of tau seeding and propagation by immunotherapy with a central tau epitope antibody. Brain 142:1736–1750. https://doi.org/10.1093/brain/awz100

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