PERK inhibitor, GSK2606414, ameliorates neuropathological damage, memory and motor functional impairments in cerebral ischemia via PERK/p-eIF2ɑ/ATF4/CHOP signaling
Author:
Funder
DHR
Publisher
Springer Science and Business Media LLC
Subject
Cellular and Molecular Neuroscience,Neurology (clinical),Biochemistry
Link
https://link.springer.com/content/pdf/10.1007/s11011-023-01183-w.pdf
Reference54 articles.
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2. Bederson JB, Pitts LH, Tsuji M, Nishimura MC, Davis RL, Bartkowski H (1986) Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 17:472–476. https://doi.org/10.1161/01.str.17.3.472
3. Bingham D, Martin SJ, Macrae IM, Carswell HVO (2012) Watermaze performance after middle cerebral artery occlusion in the rat: the role of sensorimotor versus memory impairments. J Cereb Blood Flow Metab 32:989–999. https://doi.org/10.1038/jcbfm.2012.16
4. Broughton BRS, Reutens DC, Sobey CG (2009) Apoptotic mechanisms after cerebral ischemia. Stroke 40:e331–e339. https://doi.org/10.1161/STROKEAHA.108.531632
5. Caldeira MV, Salazar IL, Curcio M, Canzoniero LMT, Duarte CB (2014) Role of the ubiquitin-proteasome system in brain ischemia: friend or foe? Prog Neurobiol 112:50–69. https://doi.org/10.1016/j.pneurobio.2013.10.003
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