Interleukin-18 is increased only in a minority of patients with active Crohn’s disease

Author:

Schmidt C.,Giese T.,Goebel R.,Schilling M.,Marth T.,Ruether A.,Schreiber S.,Zeuzem S.,Meuer S. C.,Stallmach A.

Publisher

Springer Science and Business Media LLC

Subject

Gastroenterology

Reference37 articles.

1. Zeitz M (1997) Pathogenesis of inflammatory bowel disease. Digestion 58(Suppl 1):59–61

2. Fiocchi C (1989) Inflammatory bowel disease: Etiology and pathogenesis. Gastroenterology 115:182–205

3. Breese E, Braegger CP, Corrigan CJ et al (1993) Interleukin2 and interferongammasecreting T cells in normal and diseased human intestinal mucosa. Immunology 78:127–131

4. Fuss IJ, Neurath M, Boirivant M et al (1996) Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn’s disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunology 157:1261–1270

5. Stallmach A, Marth T, Adrian T et al (2002) Increased expression of IL-12 receptor ß2 mRNA in lamina propria mononuclear cells of patients with active Crohn’s disease. Int J Colorectal Dis 17:303–310

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