Impact of age on toxicity and efficacy of 5-FU-based combination chemotherapy among patients with metastatic colorectal cancer; a pooled analysis of five randomized trials-Reference-Cited by-同舟云学术

Impact of age on toxicity and efficacy of 5-FU-based combination chemotherapy among patients with metastatic colorectal cancer; a pooled analysis of five randomized trials

Published:2019-09-06 Issue:10 Volume:34 Page:1741-1747
ISSN:0179-1958
Container-title:International Journal of Colorectal Disease
language:en
Short-container-title:Int J Colorectal Dis

Author:

Abdel-Rahman Omar^ORCID,Karachiwala Hatim

Publisher

Springer Science and Business Media LLC

Subject

Gastroenterology

Link

http://link.springer.com/content/pdf/10.1007/s00384-019-03389-w.pdf

Reference21 articles.

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3. Grande R, Natoli C, Ciancola F, Gemma D, Pellegrino A, Pavese I et al (2016) Treatment of metastatic colorectal cancer patients ≥75 years old in clinical practice: a multicenter analysis. PLoS One 11(7):e0157751-e

4. Cunningham D, Lang I, Marcuello E, Lorusso V, Ocvirk J, Shin DB, Jonker D, Osborne S, Andre N, Waterkamp D, Saunders MP (2013) Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): an open-label, randomised phase 3 trial. Lancet Oncol 14(11):1077–1085

5. Orum M, Gregersen M, Jensen K, Meldgaard P, Damsgaard EMS (2018) Frailty status but not age predicts complications in elderly cancer patients: a follow-up study. Acta Oncol 57(11):1458–1466

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