The gentamicin-collagen implant and the risk of distant metastases of rectal cancer following short-course radiotherapy and curative resection: the long-term outcomes of a randomized study

Author:

Rutkowski Andrzej,Pietrzak Lucyna,Kryński Jacek,Zając Leszek,Bednarczyk Mariusz,Olesiński Tomasz,Szpakowski Marek,Saramak Piotr,Pierzankowski Ireneusz,Hevelke Piotr,Surowski Piotr,Bujko Krzysztof

Publisher

Springer Science and Business Media LLC

Subject

Gastroenterology

Reference23 articles.

1. Peeters KC, Marijnen CA, Nagtegaal ID, Kranenbarg EK, Putter H et al (2007) Dutch Colorectal Cancer Group. The TME trial after a median follow-up of 6 years: increased local control but no survival benefit in irradiated patients with resectable rectal carcinoma. Ann Surg 5:693–701

2. Sebag-Montefiore D, Stephens RJ, Steele R, Monson J, Grieve R, Khanna S, Quirke P, Couture J, de Metz C, Myint AS, Bessell E, Griffiths G, Thompson LC, Parmar M (2009) Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial. Lancet 373:811–820

3. Breugom AJ, Swets M, Bosset JF, Collette L, Sainato A, Cionini L, Glynne-Jones R, Counsell N, Bastiaannet E, van den Broek CBM, Liefers GJ, Putter H, van de Velde CJH (2015) Adjuvant chemotherapy after preoperative (chemo)radiotherapy and surgery for patients with rectal cancer: a systematic review and meta-analysis of individual patient data. Lancet Oncol 16(2):200–207

4. Nowacki MP, Rutkowski A, Oledzki J, Chwaliński M (2005) Prospective, randomized trial examining the role of gentamycin-containing collagen sponge in the reduction of postoperative morbidity in rectal cancer patients: early results and surprising outcome at 3-year follow-up. Int J Color Dis 20:114–120

5. Rutkowski A, Zając L, Pietrzak L, Bednarczyk M, Byszek A, Oledzki J, Olesiński T, Szpakowski M, Saramak P, Chwalinski M (2014) Surgical site infections following short-term radiotherapy and total mesorectal excision: results of a randomized study examining the role of gentamicin collagen implant in rectal cancer surgery. Tech Coloproctol 18(10):921–928

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