Suppressing Tau Aggregation and Toxicity by an Anti-Aggregant Tau Fragment
Author:
Funder
DZNE
MPG
K-Hardt Foundation
Publisher
Springer Science and Business Media LLC
Subject
Neuroscience (miscellaneous),Cellular and Molecular Neuroscience,Neurology
Link
http://link.springer.com/article/10.1007/s12035-018-1326-z/fulltext.html
Reference54 articles.
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3. Devos SL, Goncharoff DK, Chen G, Kebodeaux CS, Yamada K, Stewart FR, Schuler DR, Maloney SE et al (2013) Antisense reduction of tau in adult mice protects against seizures. J Neurosci 33:12887–12897
4. ROBERSON ED, SCEARCE-LEVIE K, PALOP JJ, YAN F, CHENG IH, WU T, GERSTEIN H, YU GQ et al (2007) Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science 316:750–754
5. VON BERGEN M, FRIEDHOFF P, BIERNAT J, HEBERLE J, MANDELKOW EM, MANDELKOW E (2000) Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure. Proc Natl Acad Sci U S A 97:5129–5134
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