Small Molecule Screening Discovers Compounds that Reduce FMRpolyG Protein Aggregates and Splicing Defect Toxicity in Fragile X-Associated Tremor/Ataxia Syndrome-Reference-Cited by-同舟云学术

Small Molecule Screening Discovers Compounds that Reduce FMRpolyG Protein Aggregates and Splicing Defect Toxicity in Fragile X-Associated Tremor/Ataxia Syndrome

Published:2022-01-18 Issue:3 Volume:59 Page:1992-2007
ISSN:0893-7648
Container-title:Molecular Neurobiology
language:en
Short-container-title:Mol Neurobiol

Author:

Verma Arun Kumar,Khan Eshan,Mishra Subodh Kumar,Kumar Amit^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Neuroscience (miscellaneous),Cellular and Molecular Neuroscience,Neurology

Link

https://link.springer.com/content/pdf/10.1007/s12035-021-02697-z.pdf

Reference59 articles.

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3. Verma AK, Khan E, Bhagwat SR, Kumar A (2019) Exploring the potential of small molecule-based therapeutic approaches for targeting trinucleotide repeat disorders. Mol Neurobiol. https://doi.org/10.1007/s12035-019-01724-4

4. Warner KD, Hajdin CE, Weeks KM (2018) Principles for targeting RNA with drug-like small molecules. Nat Rev Drug Discovery 17(8):547–558. https://doi.org/10.1038/nrd.2018.93

5. Krzyzosiak WJ, Sobczak K, Wojciechowska M, Fiszer A, Mykowska A, Kozlowski P (2012) Triplet repeat RNA structure and its role as pathogenic agent and therapeutic target. Nucleic Acids Res 40(1):11–26. https://doi.org/10.1093/nar/gkr729

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