Inflammatory and Oxidative Pathways Are New Drug Targets in Multiple Episode Schizophrenia and Leaky Gut, Klebsiella pneumoniae, and C1q Immune Complexes Are Additional Drug Targets in First Episode Schizophrenia
Author:
Funder
Asahi Glass Foundation
Publisher
Springer Science and Business Media LLC
Subject
Neuroscience (miscellaneous),Cellular and Molecular Neuroscience,Neurology
Link
http://link.springer.com/content/pdf/10.1007/s12035-021-02343-8.pdf
Reference69 articles.
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2. Almulla AF, Al-Hakeim HK, Maes M (2020) Schizophrenia phenomenology revisited: positive and negative symptoms are strongly related reflective manifestations of an underlying single trait indicating overall severity of schizophrenia. CNS Spectr 20:1–10. https://doi.org/10.1017/S1092852920001182 Epub ahead of print
3. Maes M, Vojdani A, Geffard M, Moreira EG, Barbosa DS, Michelin AP, Semeão LO, Sirivichayakul S et al (2019) Schizophrenia phenomenology comprises a bifactorial general severity and a single-group factor, which are differently associated with neurotoxic immune and immune-regulatory pathways. Biomol Concepts 10(1):209–225
4. Maes M, Kanchanatawan B (2020) A generalized cognitive decline (GCoDe) partly mediates the effects of neuro-immune and neuro-oxidative toxicity on the symptomatome and lowered quality of life in (deficit) schizophrenia. Preprints 2020110523 https://doi.org/10.20944/preprints202011.0523.v1.
5. Kanchanatawan B, Sriswasdi S, Maes M (2019) Supervised machine learning to decipher the complex associations between neuro-immune biomarkers and quality of life in schizophrenia. Metab Brain Dis 34(1):267–282. https://doi.org/10.1007/s11011-018-0339-7
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