Adenovirus-Mediated Transduction of Insulin-Like Growth Factor 1 Protects Hippocampal Neurons from the Toxicity of Aβ Oligomers and Prevents Memory Loss in an Alzheimer Mouse Model-Reference-Cited by-同舟云学术

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Adenovirus-Mediated Transduction of Insulin-Like Growth Factor 1 Protects Hippocampal Neurons from the Toxicity of Aβ Oligomers and Prevents Memory Loss in an Alzheimer Mouse Model

Published:2019-11-23 Issue:3 Volume:57 Page:1473-1483
ISSN:0893-7648
Container-title:Molecular Neurobiology
language:en
Short-container-title:Mol Neurobiol

Author:

Selles Maria Clara,Fortuna Juliana T. S.,Zappa-Villar Maria F.,de Faria Yasmin P. R.,Souza Amanda S.,Suemoto Claudia K.,Leite Renata E. P.,Rodriguez Roberta D.,Grinberg Lea T.,Reggiani Paula C.,Ferreira Sergio T.^ORCID

Funder

Instituto Nacional de Ciência e Tecnologia de Neurociência Translacional

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro

International Brain Research Organization

Agencia Nacional de Promoción Científica y Tecnológica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Consejo Nacional de Investigaciones Científicas y Técnicas

National Institutes of Health

Publisher

Springer Science and Business Media LLC

Subject

Neuroscience (miscellaneous),Cellular and Molecular Neuroscience,Neurology

Link

http://link.springer.com/content/pdf/10.1007/s12035-019-01827-y.pdf

Reference71 articles.

1. Mucke L, Selkoe DJ (2012) Neurotoxicity of amyloid beta-protein: synaptic and network dysfunction. Cold Spring Harb Perspect Med 2(7):a006338. https://doi.org/10.1101/cshperspect.a006338

2. Ferreira ST, Lourenco MV, Oliveira MM, De Felice FG (2015) Soluble amyloid-beta oligomers as synaptotoxins leading to cognitive impairment in Alzheimer’s disease. Front Cell Neurosci 9:191. https://doi.org/10.3389/fncel.2015.00191

3. Selkoe DJ, Hardy J (2016) The amyloid hypothesis of Alzheimer’s disease at 25 years. EMBO Mol Med 8(6):595–608. https://doi.org/10.15252/emmm.201606210

4. de la Monte SM (2012) Contributions of brain insulin resistance and deficiency in amyloid-related neurodegeneration in Alzheimer’s disease. Drugs 72(1):49–66. https://doi.org/10.2165/11597760-000000000-00000

5. De Felice FG (2013) Connecting type 2 diabetes to Alzheimer’s disease. Expert Rev Neurother 13(12):1297–1299. https://doi.org/10.1586/14737175.2013.864824

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