Unveiling Potential Neurotoxic Mechansisms: Pb-Induced Activation of CDK5-p25 Signaling Axis in Alzheimer’s Disease Development, Emphasizing CDK5 Inhibition and Formation of Toxic p25 Species
Author:
Publisher
Springer Science and Business Media LLC
Subject
Neuroscience (miscellaneous),Cellular and Molecular Neuroscience,Neurology
Link
https://link.springer.com/content/pdf/10.1007/s12035-023-03783-0.pdf
Reference49 articles.
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2. Murumulla L, Bandaru LJM, Challa S (2023) Heavy metal mediated progressive degeneration and its noxious effects on brain microenvironment. Biol Trace Elem Res. https://doi.org/10.1007/s12011-023-03778-x
3. Balali-Mood M, Naseri K, Tahergorabi Z (2021) Toxic mechanisms of five heavy metals: mercury, lead, chromium, cadmium, and arsenic. Front Pharmacol 12:643972. https://doi.org/10.3389/fphar.2021.643972
4. Bandaru LJM, Ayyalasomayajula N, Murumulla L (2022) Defective mitophagy and induction of apoptosis by the depleted levels of PINK1 and Parkin in Pb and β-amyloid peptide induced toxicity. Toxicol Mech Methods 32:559–568. https://doi.org/10.1080/15376516.2022.2054749
5. Bandaru LJM, Ayyalasomayajula N, Murumulla L, Challa S (2022) Mechanisms associated with the dysregulation of mitochondrial function due to lead exposure and possible implications on the development of Alzheimer’s disease. Biometals an Int J role Met ions Biol Biochem Med 35:1–25. https://doi.org/10.1007/s10534-021-00360-7
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