Kynurenic Acid Restores Nrf2 Levels and Prevents Quinolinic Acid-Induced Toxicity in Rat Striatal Slices

Author:

Ferreira Fernanda Silva,Biasibetti-Brendler Helena,Pierozan Paula,Schmitz Felipe,Bertó Carolina Gessinger,Prezzi Caroline Acauan,Manfredini Vanusa,Wyse Angela T. S.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Springer Science and Business Media LLC

Subject

Neuroscience (miscellaneous),Cellular and Molecular Neuroscience,Neurology

Reference66 articles.

1. Chen Y, Guillemin GJ (2009) Kynurenine pathway metabolites in humans: disease and healthy states. Int J Tryptophan Res 2:1–19

2. Lugo-Huitrón R, Ugalde Muñiz P, Pineda B, Pedraza-Chaverrí J, Ríos C, Pérez-de la Cruz V (2013) Quinolinic acid: an endogenous neurotoxin with multiple targets. Oxidative Med Cell Longev 2013. https://doi.org/10.1155/2013/104024

3. Stone TW (1993) Neuropharmacology of quinolinic and kynurenic acids. Pharmacol Rev 45:309–379

4. Guillemin GJ (2012) Quinolinic acid, the inescapable neurotoxin. FEBS J 279:1356–1365

5. La Cruz VPD, Carrillo-Mora P, Santamaría A (2013) Quinolinic acid, an endogenous molecule combining excitotoxicity, oxidative stress and other toxic mechanisms. Int J Tryptophan Res 5:1–8

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