Genome-wide CRISPR–Cas9 Knockout Screening Reveals a TSPAN3-mediated Endo-lysosome Pathway Regulating the Degradation of α-Synuclein Oligomers
Author:
Publisher
Springer Science and Business Media LLC
Subject
Neuroscience (miscellaneous),Cellular and Molecular Neuroscience,Neurology
Link
https://link.springer.com/content/pdf/10.1007/s12035-023-03495-5.pdf
Reference65 articles.
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3. Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M (1998) alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies. Proc Natl Acad Sci U S A 95(11):6469–6473. https://doi.org/10.1073/pnas.95.11.6469
4. Dettmer U, Selkoe D, Bartels T (2016) New insights into cellular alpha-synuclein homeostasis in health and disease. Curr Opin Neurobiol 36:15–22. https://doi.org/10.1016/j.conb.2015.07.007
5. Burre J (2015) The synaptic function of alpha-synuclein. J Parkinsons Dis 5(4):699–713. https://doi.org/10.3233/JPD-150642
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