Transcutaneous Auricular Vagus Stimulation Attenuates LPS-Induced Depression-Like Behavior by Regulating Central α7nAChR/JAK2 Signaling

Author:

Wang Junying,Wang Yu,Chen Yu,Zhang Jinling,Zhang Yue,Li Shaoyuan,Zhu Haohan,Song Xingke,Hou Liwei,Wang Lei,Wang Yifei,Zhang Zixuan,Rong PeijingORCID

Funder

National Key Research and Development Program of China

Scientific and technological innovation project of China Academy of Chinese Medical Sciences

Natural Science Foundation of Beijing Municipality

the Fundamental Research Funds for the Central public welfare research institutes

Fundamental Research Funds for Central Universities of the Central South University

Publisher

Springer Science and Business Media LLC

Reference52 articles.

1. World Health Organization [WHO] (2017) Depression and other common mental disorders, Global Health Estimates. Available online at: http://apps.who.int/iris/bitstream/10665/254610/1/WHO-MSD-MER-2017.2-eng.pdf. Accessed 23 Feb 2017

2. Wu CX, Liu PH, Fu HL, Chen WT, Cui SY, Lu LM, Tang CZ (2018) Transcutaneous auricular vagus nerve stimulation in treating major depressive disorder: a systematic review and meta-analysis. Medicine (Baltimore) 97(52):e13845

3. Rong PJ, Liu J, Wang LP, Liu RP, Fang JL, Zhao JJ, Zhao Y, Wang H et al (2016) Effect of transcutaneous auricular vagus nerve stimulation on major depressive disorder: a nonrandomized controlled pilot study. J Affect Disord 195:172–179

4. Li SY, Rong PJ, Wang Y, Jin GX, Hou XB, Li SX, Xue Xiao X, Zhou W et al (2022) Comparative effectiveness of transcutaneous auricular vagus nerve stimulation vs citalopram for major depressive disorder a randomized trial. Randomized Control Trial Neuromodulation 25(3):450–460

5. Fang JL, Rong PJ, Hong Y, Fan YY, Liu J, Wang HY, Zhang GL, Chen XY et al (2016) Transcutaneous vagus nerve stimulation modulates default mode network in major depressive disorder. Biol Psychiatry 79(4):266–273

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