Chronic Hippocampal Expression of Notch Intracellular Domain Induces Vascular Thickening, Reduces Glucose Availability, and Exacerbates Spatial Memory Deficits in a Rat Model of Early Alzheimer-Reference-Cited by-同舟云学术

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Chronic Hippocampal Expression of Notch Intracellular Domain Induces Vascular Thickening, Reduces Glucose Availability, and Exacerbates Spatial Memory Deficits in a Rat Model of Early Alzheimer

Published:2018-03-26 Issue:11 Volume:55 Page:8637-8650
ISSN:0893-7648
Container-title:Molecular Neurobiology
language:en
Short-container-title:Mol Neurobiol

Author:

Galeano Pablo,Leal María C.,Ferrari Carina C.,Dalmasso María C.,Martino Adami Pamela V.,Farías María I.,Casabona Juan C.,Puntel Mariana,Do Carmo Sonia,Smal Clara,Arán Martín,Castaño Eduardo M.,Pitossi Fernando J.,Cuello A. Claudio,Morelli Laura

Funder

Agencia Nacional de Promoción Científica y Tecnológica

Consejo Nacional de Investigaciones Científicas y Técnicas

Canadian Institutes of Health Research

Publisher

Springer Science and Business Media LLC

Subject

Neuroscience (miscellaneous),Cellular and Molecular Neuroscience,Neurology

Link

http://link.springer.com/article/10.1007/s12035-018-1002-3/fulltext.html

Reference72 articles.

1. Tanzi RE, Bertram L (2005) Twenty years of the Alzheimer’s disease amyloid hypothesis: a genetic perspective. Cell 120:545–555. https://doi.org/10.1016/j.cell.2005.02.008

2. Wang ZX, Tan L, Liu J, Yu JT (2016) The essential role of soluble Abeta oligomers in Alzheimer’s disease. Mol Neurobiol 53:1905–1924. https://doi.org/10.1007/s12035-015-9143-0

3. Zoltowska KM, Berezovska O (2017) Dynamic nature of presenilin1/gamma-secretase: implication for Alzheimer’s disease pathogenesis. Mol Neurobiol 55:2275–2284. https://doi.org/10.1007/s12035-017-0487-5

4. Ables JL, Breunig JJ, Eisch AJ, Rakic P (2011) Not(ch) just development: Notch signalling in the adult brain. Nat Rev Neurosci 12:269–283. https://doi.org/10.1038/nrn3024

5. Stump G, Durrer A, Klein AL, Lutolf S, Suter U, Taylor V (2002) Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain. Mech Dev 114:153–159. https://doi.org/10.1016/S0925-4773(02)00043-6

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