The effects of melatonin supplementation in adjunct with non-surgical periodontal therapy on periodontal status, serum melatonin and inflammatory markers in type 2 diabetes mellitus patients with chronic periodontitis: a double-blind, placebo-controlled trial

Author:

Bazyar Hadi,Gholinezhad Hassan,Moradi Leila,Salehi Parvin,Abadi Faezeh,Ravanbakhsh Maryam,Zare Javid Ahmad

Funder

Ahvaz Jundishapur University of Medical Sciences

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Immunology

Reference41 articles.

1. Abdolsamadi H, Goodarzi MT, Motemayel FA, Jazaeri M, Feradmal J, Zarabadi M, Hoseyni M, Torkzaban P (2014) Reduction of melatonin level in patients with type II diabetes and periodontal diseases. J Dent Res Dent Clin Dent Prospect 8(3):160

2. Alamdari NM, Mahdavi R, Roshanravan N, Yaghin NL, Ostadrahimi A, Faramarzi E (2015) A double-blind, placebo-controlled trial related to the effects of melatonin on oxidative stress and inflammatory parameters of obese women. Horm Metab Res 47(07):504–508

3. Almughrabi O, Marzouk K, Hasanato R, Shafik S (2013) Melatonin levels in periodontal health and disease. J Periodontal Res 48(3):315–321

4. Amin AH, El-Missiry MA, Othman AI (2015) Melatonin ameliorates metabolic risk factors, modulates apoptotic proteins, and protects the rat heart against diabetes-induced apoptosis. Eur J Pharmacol 747:166–173

5. Annamalai S, Mohanam L, Alwin D, Prabhu V (2016) Effect of combination therapy of melatonin and orlistat on high fat diet induced changes in lipid profiles and liver function parameters in serum of rats. Obes Med 2:41–45

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