Elevated cerebrospinal fluid Galectin-9 is associated with central nervous system immune activation and poor cognitive performance in older HIV-infected individuals

Author:

Premeaux Thomas A.ORCID,D’Antoni Michelle L.,Abdel-Mohsen Mohamed,Pillai Satish K.,Kallianpur Kalpana J.,Nakamoto Beau K.,Agsalda-Garcia Melissa,Shiramizu Bruce,Shikuma Cecilia M.,Gisslén Magnus,Price Richard W.,Valcour Victor,Ndhlovu Lishomwa C.

Funder

Foundation for the National Institutes of Health

Swedish State support for Clinical Research

Publisher

Springer Science and Business Media LLC

Subject

Virology,Cellular and Molecular Neuroscience,Neurology (clinical),Neurology

Reference79 articles.

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2. Abdel-Mohsen M, Chavez L, Tandon R, Chew GM, Deng X, Danesh A, Keating S, Lanteri M, Samuels ML, Hoh R, Sacha JB, Norris PJ, Niki T, Shikuma CM, Hirashima M, Deeks SG, Ndhlovu LC, Pillai SK (2016) Human galectin-9 is a potent mediator of HIV transcription and reactivation. PLoS Pathog 12(6):e1005677. https://doi.org/10.1371/journal.ppat.1005677

3. Antinori A, Arendt G, Becker JT, Brew BJ, Byrd DA, Cherner M, Clifford DB, Cinque P, Epstein LG, Goodkin K, Gisslen M, Grant I, Heaton RK, Joseph J, Marder K, Marra CM, McArthur JC, Nunn M, Price RW, Pulliam L, Robertson KR, Sacktor N, Valcour V, Wojna VE (2007) Updated research nosology for HIV-associated neurocognitive disorders. Neurology 69(18):1789–1799. https://doi.org/10.1212/01.WNL.0000287431.88658.8b

4. Asakura H, Kashio Y, Nakamura K, Seki M, Dai S, Shirato Y, Abedin MJ, Yoshida N, Nishi N, Imaizumi T, Saita N, Toyama Y, Takashima H, Nakamura T, Ohkawa M, Hirashima M (2002) Selective eosinophil adhesion to fibroblast via IFN-gamma-induced galectin-9. J Immunol 169(10):5912–5918

5. Becker JT, Lopez OL, Dew MA, Aizenstein HJ (2004) Prevalence of cognitive disorders differs as a function of age in HIV virus infection. AIDS 18(Suppl 1):S11–S18

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